Department of Defense

DARPA seeks innovative materials analysis technologies enabling real-time molecular and elemental composition analysis under ambient conditions without sample preparation. Solutions must deliver revolutionary advances beyond current state-of-practice capabilities.

Fort Bragg is prototyping CASTLE, a Government-led design authority oversight model using Building Information Modeling to manage concurrent Architect-Engineer task orders. This streamlines military infrastructure delivery by embedding quality control across design-to-construction handoffs, reducing delays, field modifications, and cost overruns.

Design a consolidated 24,300-square-foot forensic laboratory integrating chemical analysis, explosives assessment, and electrical engineering capabilities. Deliverables include facility plans, MEP systems assessment, and cost estimates to eliminate infrastructure gaps constraining operational surge capacity.

The xTech|Phantum competition seeks innovative quantum sensors, quantum clocks, and photonic technologies to enhance Army position, navigation, timing, and communications capabilities while reducing dependence on GPS and improving performance in contested environments. Winners will be eligible to submit SBIR proposals under four specialized quantum and photonics topics.

DoD seeks a Government-Owned/Contractor-Operated integration facility where multiple vendors and military services can simultaneously develop joint capabilities without IP conflicts. The neutral commons accelerates multi-vendor system integration and technology fielding by eliminating structural integration barriers.

The Coast Guard seeks prototype solutions to accelerate digital workforce transformation by establishing digital role definitions, training pathways, knowledge management structures, and adoption metrics. This enables personnel to transition from paper-based workflows to digitally enabled operations that improve decision-making speed and mission readiness.

Develop advanced applied research concepts for naval space weather and plasma monitoring in the Southern Hemisphere. This challenge seeks game-changing dual-use capabilities that could accelerate Navy/Marine Corps operations while creating commercial and public benefits.

Develop AI-native air interface technology for tactical communication networks in a U.S.-India collaborative challenge. This applied research initiative seeks revolutionary dual-use concepts that could transform military communications and commercial applications.

DoD seeks low-cost unmanned maritime systems for persistent surveillance, threat detection, and rapid response in ports and coastal waters. Solutions should integrate defensive security with offensive capabilities using modular, expendable platforms across surface, subsurface, and multi-modal configurations.

This DoD funding supports patient-centered research to improve lung cancer outcomes and survivorship experiences. Projects must include patient/survivor advocates and can pursue translational or clinical research, including pilot trials.

This DoD funding supports translational lung cancer research converting promising discoveries into clinical applications. Applicants can pursue advanced preclinical studies or pilot clinical trials addressing priority research areas.

Supports early-stage, high-risk lung cancer research with potential for breakthrough discoveries. Designed for conceptually innovative projects, including a dedicated track for new faculty investigators seeking transformative advances.

The Army seeks data science innovations to advance prostate cancer research and treatment outcomes. This award supports novel analytical approaches and computational methods to improve military health and civilian medical care.

This Army research award supports early-stage investigators studying prostate cancer biology, prevention, or treatment. It funds novel scientific research to advance understanding and clinical outcomes for this disease.

This Army Medical Research Acquisition Activity (USAMRAA) award supports physician-led research to advance prostate cancer prevention, detection, and treatment. It funds innovative scientific investigations addressing this significant military and public health challenge.

The Army seeks innovative prostate cancer research to advance detection, prevention, or treatment approaches. This Idea Development Award funds early-stage scientific studies addressing unmet clinical needs in prostate cancer management.

DoD Strategic Command Offensive (SCO) Industry Day on next-generation hypersonic weapons development. Multi-day classified briefing on maneuverable hypersonic system requirements preceding OT solicitations.

DoD seeks juvenile salmonid survey research in Sinclair Inlet to monitor salmon populations near Naval Base Kitsap-Bremerton. This ecological baseline study supports integrated natural resources management and environmental stewardship at the military installation.

DoD seeks prototype space-based sensors and enabling technologies to detect, track, and maintain custody of advanced missile threats in contested environments. Solutions should advance detection algorithms, onboard processing, data fusion, fire-control tracking, resilient communications, and system survivability to TRL 7.

Monitor salmon productivity and prey availability for Cook Inlet beluga whales at Joint Base Elmendorf-Richardson to support ecosystem health assessment. This ecological research informs wildlife management and military environmental stewardship in Alaska.

Accelerate drug discovery and therapeutic development for hearing restoration following military-relevant auditory injury. This program supports preclinical and clinical research to restore hearing function in service members.

This Army Medical Research Acquisition Activity award supports mentored clinical research in vision-related medical challenges. It aims to develop clinical solutions and advance vision care capabilities through structured mentorship and research training.

xTech|Inversion seeks innovative technology solutions that accelerate military capability advancement and address complex national security challenges. The competition focuses on transitioning Army-funded research into scalable, commercially viable solutions through partnerships with non-traditional defense contractors.

Support for established neurofibromatosis researchers to lead a multi-institutional virtual academy mentoring early-career investigators. The program combines pilot research projects with structured mentorship to advance NF science and develop the next generation of research leaders.

Seeking early-stage research to develop novel therapies for Duchenne muscular dystrophy across all age groups, from infants to nonambulatory individuals. High-risk/high-reward studies with strong preliminary data that could accelerate near-term clinical outcomes.