Nanobody against NPR-C for growth disorder

Name: Nanobody against NPR-C for growth disorder
Creator: NATIONAL INSTITUTES OF HEALTH
Published: 2026-08-18T00:00:00+00:00
Keywords: GRANT

NATIONAL INSTITUTES OF HEALTHHEALTH AND HUMAN SERVICES, DEPARTMENT OF.NATIONAL INSTITUTES OF HEALTH.NATIONAL INSTITUTES OF HEALTH OLAO

AI Overview

NIH R&D contract for nanobody development against NPR-C targeting growth disorder therapeutics. Includes antigen generation, alpaca/llama immunization, phage/yeast display library screening, and VHH-Fc candidate development.

This summary is AI-generated from the official solicitation.

Key Details

Agency

NATIONAL INSTITUTES OF HEALTH

Funding Amount

—

Release Date

August 18, 2026

Due Date

August 28, 2026 (Closed)

Official Description

See attached Word document. Project Title: Nanobody against NPR-C for growth disorder

Project Overview 1.1 Background We sought to develop nanobodies (VHH) against human NPR-C with high affinity and specificity for future clinical use. These nanobodies could potentially be further developed into therapeutics for treatment of growth disorders such as achondroplasia. 1.2 Main Objectives - generation of antigens needed for immunization - immunization of Alpaca/Ilama with target antigens generate...

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