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Nanobody against NPR-C for growth disorder

NATIONAL INSTITUTES OF HEALTHHEALTH AND HUMAN SERVICES, DEPARTMENT OF.NATIONAL INSTITUTES OF HEALTH.NATIONAL INSTITUTES OF HEALTH OLAO

AI Overview

NIH R&D contract for nanobody development against NPR-C targeting growth disorder therapeutics. Includes antigen generation, alpaca/llama immunization, phage/yeast display library screening, and VHH-Fc candidate development.

This summary is AI-generated from the official solicitation.

Key Details

Agency
NATIONAL INSTITUTES OF HEALTH
Funding Amount
Release Date
August 18, 2026
Due Date
August 28, 2026

Official Description

See attached Word document. Project Title: Nanobody against NPR-C for growth disorder

  1. Project Overview 1.1 Background We sought to develop nanobodies (VHH) against human NPR-C with high affinity and specificity for future clinical use. These nanobodies could potentially be further developed into therapeutics for treatment of growth disorders such as achondroplasia. 1.2 Main Objectives - generation of antigens needed for immunization - immunization of Alpaca/Ilama with target antigens generate...
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Change History

Opportunity AddedAug 18, 2026 at 9:03 PM

Nanobody against NPR-C for growth disorder

New SAM.gov opportunity: Nanobody against NPR-C for growth disorder

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