This solicitation closed on July 21, 2026

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​Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities​

Department of StateBureau of Arms Control and Nonproliferation

AI Overview

Develop safeguards and countermeasures against misuse of AI-enabled chemical and biological models that could enable weapons proliferation. The Department of State seeks innovative solutions to identify risks and leverage nonproliferation opportunities in this emerging threat area.

This summary is AI-generated from the official solicitation.

Key Details

Agency
Department of State
Funding Amount
Up to $4,000,000
Release Date
June 29, 2026
Due Date
July 21, 2026 (Closed)

Official Description

<p>The Department of State’s Office of the Nonproliferation and Disarmament Fund (ACN/NDF) is pleased to announce an open competition for assistance awards through this Notice of Funding Opportunity (NOFO). ACN/NDF invites domestic non-profit/non-governmental organizations, educational institutions, and for-profit organizations to submit proposals for projects that will advance the mission of NDF’s efforts to identify, evaluate, and develop safeguards to counter the misuse risks enabled by the p...
View on official source

Change History

Field UpdatedJul 21, 2026 at 9:05 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

# Summary for Prospective Applicants This opportunity is open to a broad range of U.S.-based organizations including academia, nonprofits, for-profits, and small businesses, with approximately $4M available across 3 awards and no cost-sharing requirement, making it accessible to diverse applicant types without additional financial burden.

Description ChangedJul 21, 2026 at 9:05 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This opportunity expands eligible applicants to include for-profit organizations alongside nonprofits and educational institutions, and requires disclosure if partnering with other applicants responding to the same solicitation—applicants can propose addressing all objectives or a focused subset.

Funding ChangedJul 21, 2026 at 9:05 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

Funding updated: funding_amount_min

Field UpdatedJul 21, 2026 at 5:05 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This opportunity is open to a broad range of U.S.-based organizations—including universities, nonprofits, and for-profit companies—with no cost-sharing requirement, though applicants should note the vague "Others" category may require clarification and funding will be awarded as cooperative agreements or other instruments focused on science and technology research.

Description ChangedJul 21, 2026 at 5:05 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This funding opportunity opens eligibility to domestic nonprofits, educational institutions, and for-profit organizations to develop AI safeguards against chemical/biological weapons proliferation risks, with proposals required to address all or a specific subset of stated objectives and disclosure needed if partnering with another applicant to this solicitation.

Field UpdatedJul 21, 2026 at 1:05 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This opportunity is open to a broad range of U.S.-based organizations including universities, nonprofits, and for-profit entities, with no cost-sharing burden, and will be funded through cooperative agreements or other instruments to support science and technology research and development initiatives.

Description ChangedJul 21, 2026 at 1:05 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This funding opportunity expands eligibility to domestic nonprofits, educational institutions, and for-profit organizations to develop AI safeguards against chemical and biological threats, while requiring applicants to disclose any partnerships with other organizations also applying to this solicitation.

Field UpdatedJul 20, 2026 at 9:05 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This opportunity is open to a broad range of U.S.-based organizations including academic institutions, nonprofits, and for-profit entities, with no cost-sharing requirement, though applicants should note the eligibility description references "U.S. Federal Government Entities" which may create ambiguity about private sector participation.

Description ChangedJul 20, 2026 at 9:05 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This opportunity is open to domestic nonprofits, educational institutions, and for-profit organizations to develop safeguards against misuse risks from chemical and biological AI models, with proposals able to address all or specific targeted objectives and requiring disclosure of any partner organizations also submitting separate proposals.

Field UpdatedJul 20, 2026 at 5:04 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

A broad range of U.S.-based organizations can apply—including universities, nonprofits, and for-profit companies—with no cost-sharing required, though federal entities leading applications must be U.S.-based and funding will be provided through cooperative agreements or other mechanisms for science and technology research.

Description ChangedJul 20, 2026 at 5:04 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This opportunity is open to domestic non-profits, educational institutions, and for-profit organizations to develop safeguards against misuse of chemical and biological AI models, with applicants required to disclose any separate partner organizations also submitting proposals to avoid duplicative funding.

Field UpdatedJul 20, 2026 at 1:04 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This opportunity is open to a broad range of U.S.-based organizations including higher education institutions, nonprofits, and for-profit businesses, with no cost-sharing requirement, making it accessible to smaller entities with limited matching funds.

Description ChangedJul 20, 2026 at 1:04 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This opportunity opens eligibility to domestic nonprofits, educational institutions, and for-profit organizations to develop safeguards against misuse of chemical and biological AI models, with proposals requiring disclosure of any partner organizations also responding to this solicitation.

Field UpdatedJul 19, 2026 at 9:04 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This opportunity is open to a broad range of U.S.-based organizations including universities, nonprofits, and for-profit entities, with no cost-sharing requirement, but applicants should note the eligibility description mentions "U.S. Federal Government Entities" which may create ambiguity regarding state/local government participation.

Description ChangedJul 19, 2026 at 9:04 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This funding opportunity is open to domestic non-profits, educational institutions, and for-profit organizations to develop safeguards against misuse of chemical and biological AI models, with proposals limited to available funds and applicants required to disclose any separate partner submissions.

Field UpdatedJul 19, 2026 at 5:04 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

A broad range of U.S.-based organizations—including universities, nonprofits, for-profits, and small businesses—can apply for this State Department science and technology funding with no cost-sharing requirement, using either cooperative agreements or other award instruments.

Description ChangedJul 19, 2026 at 5:04 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This opportunity opens eligibility to domestic non-profits, educational institutions, and for-profit organizations to develop safeguards against misuse of chemical and biological AI models, with a requirement to disclose any partner organizations also applying to avoid duplicate funding.

Field UpdatedJul 19, 2026 at 1:04 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This opportunity is open to a broad range of U.S.-based organizations—including educational institutions, nonprofits, and for-profit companies—with no cost-sharing requirement, though it appears to prioritize federal partnerships through cooperative agreements for science and technology research.

Description ChangedJul 19, 2026 at 1:04 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This funding opportunity is open to domestic nonprofits, educational institutions, and for-profit organizations to develop safeguards against misuse risks from chemical and biological AI models, with proposals limited to available funds and applicants required to disclose any partner organizations also applying.

Field UpdatedJul 18, 2026 at 9:03 PM

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

This opportunity expands eligibility beyond small businesses to include academic institutions, nonprofits, and for-profit organizations, while requiring lead applicants to be U.S.-based and eliminating cost-sharing requirements.

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