This solicitation closed on May 13, 2026
View current Department of Defense opportunities →OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
AI Overview
Distributed protein production enables rapid, on-demand biologics creation across therapeutic, vaccine, and diagnostic domains. This innovative approach eliminates cold-chain logistics, accelerates development, and provides flexible scaling for critical medical and research applications.
This summary is AI-generated from the official solicitation.
Key Details
Official Description
On-demand distributed protein production offers significant advantages, including the creation of diverse therapies, vaccines, diagnostics, and detection biologics. It also streamlines delivery, eliminates cold-chain requirements, reduces R&D costs, and enables rapid scaling for better supply-demand matching1.
Deployable, modular BOND systems can enhance supply chain resilience and broaden medical countermeasure capabilities by enabling on-site protein production in forward-deployed locations....
Change History
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Opportunity CBD254-011 no longer available
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Status changed from Open to Open
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Q1 received a new answer clarifying that bacteriophage platforms are acceptable, but wound countermeasures are not in scope—only medical/chemical countermeasures for traditional threats qualify. SBIR-only submissions are currently accepted; STTR will be available later.
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
**Summary of Q&A Changes:** Added 1 new question (Q1) from Biocat Solutions asking whether the CBD Open Topic is appropriate for a novel bacteriophage manufacturing platform for MDR wound pathogens, and whether SBIR or STTR mechanism is better suited for partnership with USMA. **Answer pending.** All other questions (Q2-Q6) remain unchanged from previous version.
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
One new question added (Q1) regarding automated IgG purification from plasma for emerging infectious disease response. Q6 appears incomplete in the updated version. All other Q&As remain substantively unchanged from previous version.
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
# Changes to BOND Topic Q&A **No substantive changes detected.** The Updated Q&A section appears identical to the Previous Q&A section. All five Q&As (Q1-Q5) and their answers remain unchanged. Q5's answer appears truncated in both versions but shows no new information or clarifications added.
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Status changed from Pre-Release to Open
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Q&A section updated
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Close Date changed from 2026-03-04 to 2026-04-29
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Open Date changed from 2026-02-11 to 2026-04-01
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Close Date changed from 2026-02-25 to 2026-03-04
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Open Date changed from 2026-02-04 to 2026-02-11
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Close Date changed from 2026-02-11 to 2026-02-25
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Open Date changed from 2026-01-21 to 2026-02-04
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Q&A section updated
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Close Date changed from 2026-02-04 to 2026-02-11
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Open Date changed from 2026-01-14 to 2026-01-21
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Q&A section updated
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Content updated: description, objective, phase_1_description, phase_2_description, phase_3_description
OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
Q&A section updated
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