This solicitation closed on May 13, 2026

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CBD254-006CancelledSBIR

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Department of DefenseCBD

AI Overview

Develop portable, lightweight SERS sampling tickets to enhance chemical and biological threat detection for military personnel, enabling more sensitive and selective identification of materials with minimal sample requirements compared to current handheld Raman detectors. These innovative coupons address variability challenges in spectroscopic measurements, providing a compact solution for rapid threat assessment in specialized CBRN units.

This summary is AI-generated from the official solicitation.

Key Details

Agency
Department of Defense
Funding Amount
Release Date
November 18, 2025
Due Date
May 13, 2026 (Closed)
Phase I Award
209575.00
Phase II Award
1397165.00

Official Description

The Department of Defense has fielded several handheld Raman detectors over the past 15 years to support specialized chemical, biological, radiological, and nuclear (CBRN) units across the services and Special Operations forces. These detectors typically contain very large libraries (in the thousands) of solid and liquid chemicals (including toxins, as chemicals of biological origin) that are identifiable with the device. However, these devices typically require a “bulk” amount of liquid or soli...

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Change History

Opportunity RemovedMay 13, 2026 at 4:58 PM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Opportunity CBD254-006 no longer available

Status ChangedMay 13, 2026 at 1:10 AM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Status changed from Open to Open

Q&A UpdatedApr 23, 2026 at 11:34 AM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

# Q&A Changes Summary **Q8 was added** with 5 detailed technical questions about SERS coupon specifications: - Target cost range and single-use vs. reusable format - Handheld detector optical/mechanical compatibility parameters - Detection-limit improvement targets for Phase I - Coupon reusability and cleaning protocols - Environmental/handling conditions tolerance **Note:** Q8's answer appears truncated in the updated version ("Topic: Novel Sampling Tickets..."), so the government response to these 5 sub-questions is incomplete/pending.

Q&A UpdatedApr 22, 2026 at 7:37 PM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

# Q&A Changes Summary **New Question Added:** Deadline clarification—June 3rd is for 2026 solicitation (Release 1), while May 13th applies to the delayed 2025 solicitation (FY25.4 Release 12) covering topic CBD254-006. **Key clarifications on existing topics:** - Cost target: $10 per substrate or less at production scale - Format: Single-use disposable coupons (not reusable) - Substrate compatibility: One platform substrate acceptable; separate regions for 785/830 nm vs. 1064 nm on same substrate allowed

Q&A UpdatedApr 21, 2026 at 7:36 PM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

# Q&A Changes Summary **New Answer Added:** - **Q1 (Swept-source Raman compatibility):** Government clarified that while swept-source lasers could potentially be used with developed substrates, this topic is **substrate development only** — not alternative detector architectures. **Previously Pending Answer Now Provided:** - **Q7-1 (Cost & Use Model):** Government specified coupons must be **single-use disposable at ≤$10/unit** production cost. **Note:** Q7-2 through Q7-5 remain unanswered in both versions (optical parameters, detection-limit guidance, reusability, environmental conditions).

Q&A UpdatedApr 16, 2026 at 1:01 AM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

# Summary of Q&A Changes **New Question Added:** - Q1: Inquiry about alternative Raman architecture (multiplexed swept-source Raman) and alignment with topic CBD254-006. Government response clarifies topic scope focuses on SERS substrate development for traditional fielded handheld Raman detectors. **No substantive answer changes** – all previous Q&As (Q2-Q7) remain identical, covering: enhancement mechanisms, market volume (hundreds of thousands/year), multi-wavelength compatibility (785/830/1064nm), Phase I-only submissions, cost target ($10/unit or less), physical specifications (5-15mm size, >100µm laser spot, 2-300mm working distance), and single-use disposable format.

Status ChangedApr 14, 2026 at 11:32 AM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Status changed from Pre-Release to Open

Date ChangedMar 19, 2026 at 12:15 PM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Close Date changed from 2026-03-04 to 2026-04-29

Date ChangedMar 19, 2026 at 12:15 PM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Open Date changed from 2026-02-11 to 2026-04-01

Date ChangedFeb 3, 2026 at 12:24 AM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Close Date changed from 2026-02-25 to 2026-03-04

Date ChangedFeb 3, 2026 at 12:24 AM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Open Date changed from 2026-02-04 to 2026-02-11

Date ChangedJan 20, 2026 at 4:10 PM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Close Date changed from 2026-02-11 to 2026-02-25

Date ChangedJan 20, 2026 at 4:10 PM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Open Date changed from 2026-01-21 to 2026-02-04

Date ChangedJan 12, 2026 at 8:06 PM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Close Date changed from 2026-02-04 to 2026-02-11

Date ChangedJan 12, 2026 at 8:06 PM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Open Date changed from 2026-01-14 to 2026-01-21

Q&A UpdatedJan 8, 2026 at 1:53 PM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Q&A section updated

Description ChangedJan 8, 2026 at 1:53 PM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Content updated: description, objective, phase_1_description, phase_2_description, phase_3_description

Q&A UpdatedJan 7, 2026 at 10:05 PM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Q&A section updated

Description ChangedJan 7, 2026 at 10:05 PM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Content updated: description, objective, phase_1_description, phase_2_description, phase_3_description

Q&A UpdatedJan 7, 2026 at 12:17 AM

Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials

Q&A section updated

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