Department of Defense

The Navy seeks retrofit technology to enhance situational awareness for aircraft towing crews across shipboard and land-based operations. Solutions must integrate real-time collision alerts or intervention systems with existing tow tractors to reduce mishaps, equipment damage, and mission delays.

The Navy seeks a bi-directional Cross-Domain Solution (CDS) guard software for secure data exchange across naval aircraft and ships. The solution must run on affordable, modular hardware with rapid rule-set updates to enable faster NSA certification while reducing acquisition and sustainment costs.

This RFP seeks an enhanced cable connector solution to address common failure points in electronics systems exposed to thermal and mechanical stress. The solution must overcome limitations of current potting, rework, and alternative joining methods while remaining practical for existing designs and densely populated boards.

This RFP seeks to validate additive manufacturing technologies for flexible electronics and advanced packaging to reduce costs and lead times in high-mix, low-volume production. The effort aims to establish reliability data for 3D-printed substrates and interconnects as viable alternatives to traditional manufacturing methods for Department of War microelectronic systems.

This RFP seeks development of real-time 3D imaging and tracking algorithms for directed energy systems to improve aimpoint maintenance on low-flying targets in cluttered environments. The solution must process complex 3D imagery efficiently enough to operate at high framerates while compensating for atmospheric disturbances.

The Air Force is seeking innovative composite joint technologies that balance geometric flexibility with high structural performance while reducing costs for autonomous air vehicles and advanced weapons systems. The effort aims to develop scalable manufacturing processes for carbon fiber pi-joints that overcome current tradeoffs between customizable design and mechanical durability.

This SBIR seeks development of an ultra-sensitive quantum telemetry receiver using Rydberg sensors to overcome DoD spectrum constraints and interference challenges. The prototype will deliver superior signal detection and operational flexibility while reducing reliance on expensive licensed frequency bands and supporting next-generation command and control systems.

This RFP seeks an open-architecture software and hardware toolkit to rapidly modernize legacy aircraft by delivering processed sensor data to operators in real-time. The solution bypasses slow manual processes to improve pilot situational awareness and accelerate fielding of next-generation capabilities while maintaining airworthiness standards.

This RFP seeks rapid weapons integration solutions for F-35 aircraft to dramatically accelerate munitions deployment timelines. The effort addresses critical capability gaps by enabling faster software and weapons updates while expanding magazine capacity and fires options across the Air Force, Air National Guard, and Reserve fleets.

This RFP seeks a modular weapons integration architecture for F-16 aircraft that dramatically accelerates munitions integration timelines. The solution will streamline legacy software processes to enable rapid deployment of new weapons and software updates, addressing critical capability gaps against evolving threats.

The Air Force seeks high-temperature semiconductor transistors operating at 500°C+ to enable reliable electronics in extreme heat environments and electronic warfare applications, addressing current commercial limitations where existing transistors fail above 250°C.

This RFP seeks radiation-hardened high-voltage power switches (200V–800V) capable of operating in contested space environments. The technology must enable advanced spacecraft capabilities—electric propulsion, edge computing, and solar power beaming—while maintaining efficiency and minimal size/weight constraints.

This DoD funding supports innovative research to transform Alzheimer's diagnosis and disease monitoring. Projects must demonstrate non-incremental solutions that overcome barriers to diagnosis and prognosis, with preliminary data and community collaboration required.

Supports transformative research to identify and validate risk factors for Alzheimer's disease and develop prevention strategies. Projects must advance understanding of environmental, genetic, or lifestyle risks and propose actionable solutions to reduce AD/ADRD development.

This DoD program funds clinical research and trials testing new care interventions for Alzheimer's disease and related dementia. Projects must demonstrate preliminary data, involve community collaboration, and address practical care solutions beyond drug testing.

DoD seeks prototype development of an affordable, extended-range cruise missile (1,000+ nautical miles) costing under $300,000 per unit. The system must maintain precision strike capability and low-radar-signature survivability while using commercially available materials and modular design to solve critical munitions stockpile depth constraints.

DARPA seeks breakthrough inertial navigation sensors that break through decades of MEMS performance limits using revolutionary physics like electromagnetically levitated proof masses and nonlinear resonators. The program demands tight integration of novel sensor architectures with adaptive control systems for tactical and unmanned applications.

Develop high-impact ideas advancing kidney cancer understanding and patient outcomes through well-formulated research hypotheses. Supports single or partnered investigator teams with strong kidney cancer research backgrounds.

This DoD program mentors early-career kidney cancer researchers through intensive virtual training, peer networking, and personalized mentorship. It aims to develop the next generation of cutting-edge kidney cancer researchers and accelerate discovery of new patient treatments.

DARPA BTO seeks novel biological technologies that revolutionize warfighter protection by leveraging biological properties and processes. Evolutionary improvements to existing practices are excluded; only truly innovative approaches will be considered.

Develop ALS therapeutics from preclinical validation through FDA IND-enabling studies. This award accelerates drug candidates toward clinical testing while requiring parallel development of mechanism-specific biomarkers for improved patient selection and trial design.

DoD seeks breakthrough breast cancer research with high clinical potential, supporting projects from preclinical through early clinical stages. Applications must address priority research challenges and include consumer advocates as core team members.

Develop and validate clinical biomarkers and outcome measures to improve ALS clinical trials, including digital health tools like wearables and AI-enabled monitoring. Projects should incorporate patient community input and may target specific ALS subtypes or therapeutic classes.

This DoD funding supports high-risk, hypothesis-driven research to discover new ALS drugs and therapies. Applications emphasizing novel approaches can succeed without preliminary data, enabling bold therapeutic innovation.

This DoD award funds multidisciplinary, multi-institutional consortia addressing transformative breast cancer research challenges. Led by up to five PIs and consumer advocates, projects must tackle major problems requiring collaborative breakthroughs that single investigators cannot achieve.