Federal Innovation Funding Briefing: Week of May 30, 2026 – June 5, 2026

This RFP seeks a computational system using protein language models to rapidly characterize pathogen-host interactions from sequence data alone, enabling faster threat assessment and therapeutic response when novel pathogens emerge. The capability must predict protein interactions across pathogen classes, work on unseen pathogens, and deliver comprehensive analysis within one hour on standard hardware.

This SBIR XL seeks integrated manufacturing solutions for compact Rydberg-based RF receivers that operate across broad frequency bands with high sensitivity. The technology addresses the gap between laboratory prototypes and deployable systems by combining photonic components with low-latency control architecture for wideband signal processing.

DARPA seeks development of high-energy-density, air-independent rechargeable batteries for military applications where oxygen is unavailable—such as underwater, high-altitude, or space operations. Proposals must demonstrate specific energy exceeding 1 kWh/kg with electrical rechargeability over multiple charge cycles.

This RFP seeks engineering solutions to enhance cognitive performance and physiological recovery in high-demand operational environments where sleep is restricted. The capability aims to address performance degradation caused by sleep deprivation by supporting critical brain functions like waste clearance and synaptic plasticity.

This RFP seeks biomanufactured thermal interface materials (TIMs) to improve heat dissipation in high-density electronics, drones, and battery systems. The solution must balance thermal conductivity with electrical insulation while offering cost-effective, sustainable alternatives to traditional materials.

Develop advanced fibers, connectors, and optical interfaces for distributed laser weapon systems to defend expeditionary airfields and counter unmanned aircraft. The Navy seeks prototype development and integration demonstrations using modular, open-systems architectures.

The Navy seeks commercial partners to develop and demonstrate next-generation hypersonic prototype systems, including integrated payload, booster, and mission systems with advanced manufacturing approaches for operational deployment.

The Navy seeks a multi-vendor satellite imagery scheduling optimization platform that integrates commercial providers into a unified system to enhance maritime domain awareness. The solution must dynamically adapt to weather, prioritize time-critical tasking, and reduce reliance on single-source imagery while minimizing costs and redundant collections.

The Navy seeks an AI-enabled Terminal Defense Weapon System Coordinator that decouples rapid weapon system upgrades from lengthy combat system development cycles. The solution will coordinate real-time engagement management across multiple defense systems while maintaining cybersecurity and integration with ship combat systems.

The Army seeks autonomous and minimally-manned ground and aerial systems for sustainment and recovery in contested environments where GPS and communications are degraded. Solutions must operate with minimal oversight across payload transport, power generation, refueling, and vehicle recovery to reduce soldier exposure and maintain mission continuity.